Bioinformatics Platform Service

Creative Biolabs perfectly utilizes next-generation sequencing technology to provide high-throughput, low-cost, fast and efficient bioinformatics platform service. Creative Biolabs assists customers with complex data processing of biological information and helps customers master data analysis techniques and methods. The bioinformatics platform provides professional training in sequencing and analysis knowledge, as well as corresponding data analysis service to meet the needs of customers for sequencing data analysis. Creative Biolabs provides support for domestic and foreign customers in the application of bioinformatics and biostatistics in research projects. Bioinformatics platform of Creative Biolabs provides service about bioinformatics software usage, data analysis, interpretation of statistical significance of computational results. We focuses on consulting and supporting high-throughput sequencing project design and data analysis to accelerate research project progress.

We provide but are not limited to:

1. Analysis service of genome sequencing data. Creative Biolabs can perform individual DNA sequencing service and subsequent bioinformatics analysis. Through genome-sequencing genetics and disease genomics, Creative Biolabs can quickly and conveniently screen out genome-wide genetic variations and find new disease-causing and susceptible genes. Creative Biolabs can help customers fully explore gene variation, including single base mutation, insert-deletion mutation, copy number variation and structural variation.
• Standard information analysis service. The service include the following: (1) Remove joints and low quality sequences from raw data; (2) Data output statistics and quality control assessment; (3) The assessment of comparison rate and data pollution; (4) Mutation detection of SNP and InDel; (5) Mutation detection of CNV and SV; (6) Analysis of variation differences among multiple local populations.
• Customized information analysis service. Creative Biolabs can customize the information analysis content according to the specific requirements of customers.
2. Analysis service of transcriptome sequencing data. Creative Biolabs can assist customers to explore the dynamic process of gene expression in cells. Analyzing genome-wide expression levels can help customers better understand this biological process and explore new indications for drugs. Creative Biolabs can easily and quickly obtain the entire transcriptional expression level of a specific cell under a certain functional state by using RNA-Seq.
• Standard information analysis service. The service include the following: (1) Remove joints and low quality sequences from raw data; (2) Data output statistics and quality control assessment; (3) Gene expression quantification; (4) Sample correlation analysis; (5) Analysis of gene differential expression; (6) Cluster analysis of different gene expression patterns; (7) Pathway(KEGG) significance analysis of differential genes; (8) Identify variable splicing of genes.
• Customized information analysis service. Creative Biolabs can customize the information analysis content according to the specific requirements of customers.
3. Analysis service of apparent group sequencing data. Creative Biolabs can provide DNA methylation service to obtain important epigenetic marker information. Through whole genome bisulfite sequencing (WGBS) and simplified bisulfite sequencing technology, Creative Biolabs can obtain genome-wide methylation levels of all C sites and conduct spatio-temporal specificity studies of epigenetics. Creative Biolabs provides analysis of high-precision methylation modification patterns for specific species to help clients analyze basic mechanisms include cell differentiation and tissue development to achieve human health and disease research purposes.
• Standard information analysis service. The service include the following: (1) Remove joints and low quality sequences from raw data; (2) Data output statistics and quality control assessment; (3) Compare reads processed by bisulfite to the genome; (4) Evaluation of C base methylation level; (5) Differential methylation region analysis.
• Customized information analysis service. Creative Biolabs can customize the information analysis content according to the specific requirements of customers.

References

1. Wooller SK, et al. Bioinformatics in translational drug discovery. Biosci Rep. 2017 Jul 7;37(4):BSR20160180.
2. Oliver GR, et al. Bioinformatics for clinical next generation sequencing. Clin Chem. 2015 Jan;61(1):124-35.

*For Research Use Only. Not for use in diagnostic procedures.