Subcutaneous Tumor Modeling in Mouse
In vivo experiments on mouse subcutaneous tumors are a common way to establish tumor models, which are of great value to the basic and applied research of various tumors. Nowadays, the in vivo experiment of mouse subcutaneous tumors is a mature technology. Subcutaneous tumor modelling is commonly used in the construction of various tumor models such as osteosarcoma, lung cancer, breast cancer, colon cancer, etc. So subcutaneous tumor modelling provides a good way for further research on the characteristics, mechanisms, and drug application of various tumors research. Compared with the construction of other tumor models such as cell lines culture, the in vivo experiment of mouse subcutaneous tumors can simulate the environment in the human body to the greatest extent, so that the transplanted tumor can retain the malignant characteristics and histopathological and biological characteristics of the original host. It is a good simulation of the incidence of cancer on the native host.
Based on the tumor model established by the mouse subcutaneous tumor in vivo experiment, we can further perform growth curve determination, pathological examination, immunohistochemistry detection, cytokine detection, flow cytometry detection, fluorescence imaging detection in vivo, DNA sequencing and mutation analysis, and drug effect detection, etc. In vivo, experimental models of mouse subcutaneous tumors have a high success rate and stable passage, which is an ideal modeling method.
Fig1. The flow chart of subcutaneous tumor modeling in mouse.
We focus on meticulous, precise, high success rate, and provide services for subcutaneous tumor modeling in mouse. Our service purpose is to provide detailed and accurate subcutaneous tumor modeling in mouse through a complete mouse surgery and breeding platform, and help all tumor researchers in the construction and culture of tumor mouse models and subsequent experiments. Your success is our goal to pay every effort to work on.
We provide but are not limited to:
- A well-designed experiment protocol with all kinds of following tests you may need.
- Experienced employees which are skilful in tumor culture, we can guarantee the success rate of the operation is high which can avoid the waste of tumor samples.
- A high-end feeding room and operating room with a full-powered purification system will make sure there will be no trouble during rising and tumor culture.
Advantages of Subcutaneous Tumor Modeling in Mouse:
- The mouse model will provide a perfect growing environment of tumor tissue.
- As a basic process during the research stream, mouse subcutaneous in vivo can create the sample for the following experiment.
- Subcutaneous tumor modeling makes seed cells preservation easy.
- Subcutaneous tumor modeling can make your multiply working plan more organized to save your time.
We can do furthermore:
- We can also offer the following experiments like western blot, sequencing survey, and so on.
- We can deal with the tumor samples from models or clinical separation samples.
References
- Garcia-Fabiani M B. An Optimized Protocol for In Vivo Analysis of Tumor Cell Division in a Sleeping Beauty-Mediated Mouse Glioma Model. STAR Protocols, 2020:100044.
- Ganguly T. Evaluation of Two Optical Probes for Imaging the Integrin αvβ6 In Vitro and In Vivo in Tumor-Bearing Mice. Molecular Imaging & Biology, 2020(6).
- S Kesserwan. Advancing continuous subcutaneous insulin infusion in vivo: New insights into tissue challenges. Journal of Biomedical Materials Research Part A, 2020.
- Jie Tao. The regulatory role of Annexin 3 in a nude mouse bearing a subcutaneous xenograft of MDA-MB-231 human breast carcinoma. Pathology, research and practice, 2018.
*For Research Use Only. Not for use in diagnostic procedures.